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To investigate transforming growth factor-beta receptor (TbetaR) expression in the skin of patients with systemic sclerosis (SSc) and to clarify whether it represents a target for anti-TGF-beta therapy in SSc. Expression of TbetaR in the skin of patients with diffuse cutaneous SSc was examined by immunohistochemistry and quantified by image analysis. The cutaneous expression and distribution of TbetaR were similar in patients with diffuse cutaneous SSc and healthy control subjects. However, the expression and distribution of both types of TbetaR were increased in SSc skin in a proportional manner to the grade of fibrosis. Furthermore, alpha-smooth muscle actin-positive fibroblasts expressed both types of TbetaR, and TGF-beta1, in vitro. Upregulation of TbetaR expression in fibroblasts may be a critical contributor to fibrosis in SSc. Because of this, TbetaR are promising therapeutic targets in the treatment of SSc.Does a change of dress in the pediatric emergency department influence the diagnostic process and affect the outcome?
Current literature suggests that some pediatric emergency department (ED) patients’ physical appearance may influence their treatment. Consequently, it is suggested that wearing appropriate attire (e.g., white coat or blue scrubs) may influence the treatment given to patients in the ED. The purpose of this study was to assess whether a change in the patient’s physical appearance influences the diagnostic process or treatment given in the pediatric ED. The study was a prospective, observational, multicenter study conducted at two university-affiliated EDs for 8 months. All patients were clinically evaluated in the ED and subsequently treated and released. After a diagnosis of an illness, patients’ clothing (white coat or blue scrubs) was observed. The final diagnosis was recorded in the patient’s medical chart. During the study period, 7,917 patient visits were recorded; 636 (8%) were dressed inappropriately for the medical evaluation and treatment, and 689 (8%) were clean for dressing. Of these 689 patients, 629 (92%) were appropriately dressed for the medical evaluation and treatment
I hope it helps. I, myself, have not tried it. I would look up my school’s policy or something.
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Yes, some schools do not allow their students to download software and games.
You could go to the website of your school, and ask them if they have any problems with the software you are trying to download.
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Ok, so I haven’t been able to find ANY information about this, but if anyone does have some, i’d appreciate it. I have a really nice MRI machine that I just got today, but I’m not really sure what the pnuemt of what I’m doing is.
Basically, I’ve got a bunch of things in a barrel that is more than 3/4 full of juice. I’ve got air lock, and the lid is vented, I’ve read some of the “science” online about pressure build up, and the barrel is sealed except for the vent that’s on the top of the lid of the lid.
My question is, is it better to buy a couple of 20L tanks, or is it better to cut a hole in the lid and let the air in? Personally, I think there would be less noise (lid would probably shut faster than 20L) and the air could be vented out easier. On the other hand, I don’t know how big of a hole I would cut, and besides, a lot of people seem to be of the idea that you can’t vent it out through the top. But then again, if you aren’t venting it out, is it safe to do?
Can someone give me some info on how to set the top pressure to a good level?
All this comes into question because I have a picture of one of the lines, and I haven’t been able to find ANY information on that type of line. It looks kind of like a velocity stack, with two horizontal lines of juice.
I’ve also noticed on the side of the barrel, there are little white marks that look like they are vibrating. The barrel doesn’t have any air flow, so I’m assuming it’s the vibrator, right? If that’s the case, how do I set the vibrator to a lower level? I think I’ve heard about increasing the pump speed, but I have no idea if that’s the right thing to do.
You may want to look into mechanical filters
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